Nuclear receptor ERRα contributes to castration-resistant growth of prostate cancer via its regulation of intratumoral androgen biosynthesis

Enhanced intratumoral androgen biosynthesis and persistent androgen receptor (AR) signaling are key factors responsible for the relapse growth of castration-resistant prostate cancer (CRPC). Residual intraprostatic androgens can be produced by de novo synthesis of androgens from cholesterol or conve...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Xu, Zhenyu, Ma, Taiyang, Zhou, Jianfu, Gao, Weijie, Li, Youjia, Yu, Shan, Wang, Yuliang, Chan, Franky Leung
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086365/
https://ncbi.nlm.nih.gov/pubmed/32226548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35589
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