A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance

Background: Dysregulated microRNA (miRNA) expression in cancer can act as a key factor that modifies biological processes, including chemoresistance. Our study aimed to identify the miRNAs associated with gemcitabine (GEM) resistance in pancreatic ductal adenocarcinoma (PDAC) and to explore the pote...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Meng, Qingcai, Liang, Chen, Hua, Jie, Zhang, Bo, Liu, Jiang, Zhang, Yiyin, Wei, Miaoyan, Yu, Xianjun, Xu, Jin, Shi, Si
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086345/
https://ncbi.nlm.nih.gov/pubmed/32226532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.40566
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