Promoter Hypermethylation of CHODL Contributes to Carcinogenesis and Indicates Poor Survival in Patients with Early-stage Colorectal Cancer

Aims: Aberrant hypermethylation of CpG islands is an important hallmark of colorectal cancer (CRC). We previously utilized methyl-DNA immunoprecipitation assays to identify a novel methylated gene, chondrolectin (CHODL), preferentially methylated in human CRC. In this study, we examined the epigenet...

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Udgivet i:J Cancer
Main Authors: Zhang, Xinyue, Wu, Kaiming, Huang, Yuhua, Xu, Lixia, Li, Xiaoxing, Zhang, Ning
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086254/
https://ncbi.nlm.nih.gov/pubmed/32226505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.38815
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