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Oral exposure of sulpiride promotes the proliferation of Brown-Norway rat prostates

Abstract: The aim of the present study was to establish an animal model of prostatic hyperplasia to explore the mechanisms of this disease. Sulpiride, a specific type 2 dopamine receptor antagonist, causes prostate toxicity by stimulating prolactin (PRL) production. Male Brown-Norway (BN) rats were...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zheng, Chengcheng, Luo, Yongwei, Chen, Ying, Chen, Dingshi, Shao, Congcong, Huang, Dongyan, Zhu, Jing, Mao, Xiaoyan, Li, Lei, Sun, Zuyue
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086227/
https://ncbi.nlm.nih.gov/pubmed/32256734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8521
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