Various subtypes of phosphodiesterase inhibitors differentially regulate pulmonary vein and sinoatrial node electrical activities

Phosphodiesterase (PDE)3-5 are expressed in cardiac tissue and play critical roles in the pathogenesis of heart failure and atrial fibrillation. PDE inhibitors are widely used in the clinic, but their effects on the electrical activity of the heart are not well understood. The aim of the present stu...

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Bibliographic Details
Published in:Exp Ther Med
Main Authors: Lin, Yung-Kuo, Cheng, Chen-Chuan, Huang, Jen-Hung, Chen, Yi-Ann, Lu, Yen-Yu, Chen, Yao-Chang, Chen, Shih-Ann, Chen, Yi-Jen
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086206/
https://ncbi.nlm.nih.gov/pubmed/32256760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8495
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