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A previously identified apoptosis inhibitor iASPP confers resistance to chemotherapeutic drugs by suppressing senescence in cancer cells

Cellular senescence is terminal cell cycle arrest that represents a prominent response to numerous anticancer therapies. The oncogene inhibitor of the apoptosis-stimulating protein of p53 (iASPP) plays essential roles in regulating cellular drug response by inhibiting apoptosis. However, whether or...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Huayi, Zhang, Wenxin, Zhao, Kunming, Zhao, Dong, Zheng, Shanliang, Hu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086043/
https://ncbi.nlm.nih.gov/pubmed/32005663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011411
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