The Shb scaffold binds the Nck adaptor protein, p120 RasGAP, and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2

Eph receptors are a family of receptor tyrosine kinases that control directional cell movement during various biological processes, including embryogenesis, neuronal pathfinding, and tumor formation. The biochemical pathways of Eph receptors are context-dependent in part because of the varied compos...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wagner, Melany J., Hsiung, Marilyn S., Gish, Gerald D., Bagshaw, Rick D., Doodnauth, Sasha A., Soliman, Mohamed A., Jørgensen, Claus, Tucholska, Monika, Rottapel, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086039/
https://ncbi.nlm.nih.gov/pubmed/32060095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009276
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