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EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak

EphB receptors and their ephrinB ligands transduce bidirectional signals that mediate contact-dependent axon guidance primarily by promoting growth cone repulsion. However, how EphB receptor-mediated forward signaling induces axonal repulsion remains poorly understood. Here, we identify Nck and Pak...

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Main Authors: Srivastava, Nishi, Robichaux, Michael A., Chenaux, George, Henkemeyer, Mark, Cowan, Christopher W.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587115/
https://ncbi.nlm.nih.gov/pubmed/23147113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.11.003
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