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Apolipoprotein E and Oxidative Stress in Brain with Relevance to Alzheimer Disease

Inheritance of apolipoprotein E4 (APOE4) is a major risk factor for development of Alzheimer disease (AD). This lipoprotein, in contrast to apoE2, has arginine residues at positions 112 and 158 in place of cysteines in the latter isoform. In apoE3, the Cys at residue 158 is replaced by an arginine r...

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Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Butterfield, D. Allan, Mattson, Mark P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085980/
https://ncbi.nlm.nih.gov/pubmed/32036033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104795
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