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Accurate annotation of human protein-coding small open reading frames

Functional protein-coding small open reading frames (smORFs) are emerging as an important class of genes. However, the number of translated smORFs in the human genome is unclear because proteogenomic methods are not sensitive enough, and, as we show, Ribo-Seq strategies require additional measures t...

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Detalles Bibliográficos
Publicado en:Nat Chem Biol
Main Authors: Martinez, Thomas F., Chu, Qian, Donaldson, Cynthia, Tan, Dan, Shokhirev, Maxim N., Saghatelian, Alan
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085969/
https://ncbi.nlm.nih.gov/pubmed/31819274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0425-0
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