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Accurate annotation of human protein-coding small open reading frames

Functional protein-coding small open reading frames (smORFs) are emerging as an important class of genes. However, the number of translated smORFs in the human genome is unclear because proteogenomic methods are not sensitive enough, and, as we show, Ribo-Seq strategies require additional measures t...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Martinez, Thomas F., Chu, Qian, Donaldson, Cynthia, Tan, Dan, Shokhirev, Maxim N., Saghatelian, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085969/
https://ncbi.nlm.nih.gov/pubmed/31819274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0425-0
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