Confocal Raman Spectral Imaging Study of DAPT, a γ-secretase Inhibitor, Induced Physiological and Biochemical Reponses in Osteosarcoma Cells

Confocal Raman microspectral imaging was adopted to elucidate the cellular drug responses of osteosarcoma cells (OC) to N-[N-(3, 5-difluorophenyl acetyl)-L-alanyl]-sphenylglycine butyl ester (DAPT), a γ-secretase inhibitor, by identifying the drug induced subcellular compositional and structural cha...

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Bibliographic Details
Published in:Int J Med Sci
Main Authors: Li, Jie, Wang, Rui, Qin, Jie, Zeng, Haishan, Wang, Kaige, He, Qingli, Wang, Difan, Wang, Shuang
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085205/
https://ncbi.nlm.nih.gov/pubmed/32210707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.43506
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