DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch Signaling

Advances in the understanding of growth hormone-producing adenomas (GHomas) are ongoing, but current therapy is limited by moderate and variable efficacy and in need of life-long treatment. In this study, the molecular signaling pathway related to GHoma was investigated by proteomics and transcripto...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Oncol
Prif Awduron: Feng, Jie, Wang, Jianpeng, Liu, Qian, Li, Jiye, Zhang, Qi, Zhuang, Zhengping, Yao, Xiaohui, Liu, Chunhui, Li, Yangfang, Cao, Lei, Li, Chuzhong, Gong, Lei, Li, Dan, Zhang, Yazhuo, Gao, Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Oncology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718711/
https://ncbi.nlm.nih.gov/pubmed/31508369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00809
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