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Cordycepin Resensitizes T24R2 Cisplatin-Resistant Human Bladder Cancer Cells to Cisplatin by Inactivating Ets-1 Dependent MDR1 Transcription

Tumor cell resistance to anti-cancer drugs is a major obstacle in tumor therapy. In this study, we investigated the mechanism of cordycepin-mediated resensitization to cisplatin in T24R2 cells, a T24-derived cell line. Treatment with cordycepin or cisplatin (2 μg/mL) alone failed to induce cell deat...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Oh, Sang-Seok, Lee, Ki Won, Madhi, Hamadi, Jeong, Jin-Woo, Park, Soojong, Kim, Minju, Lee, Yerin, Han, Hyun-Tak, Hwangbo, Cheol, Yoo, Jiyun, Kim, Kwang Dong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084876/
https://ncbi.nlm.nih.gov/pubmed/32131547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051710
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