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Contributions of DNA Damage to Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of neurodegenerative disease. Its typical pathology consists of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrillary tangles. Mutations in the APP, PSEN1, and PSEN2 genes increase Aβ production and aggregation, and thus cause ear...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084447/ https://ncbi.nlm.nih.gov/pubmed/32121304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051666 |
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