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Contributions of DNA Damage to Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of neurodegenerative disease. Its typical pathology consists of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrillary tangles. Mutations in the APP, PSEN1, and PSEN2 genes increase Aβ production and aggregation, and thus cause ear...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lin, Xiaozeng, Kapoor, Anil, Gu, Yan, Chow, Mathilda Jing, Peng, Jingyi, Zhao, Kuncheng, Tang, Damu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084447/
https://ncbi.nlm.nih.gov/pubmed/32121304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051666
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