Regulation of Small GTPase Rab20 by Ikaros in B-Cell Acute Lymphoblastic Leukemia

Ikaros is a DNA-binding protein that regulates gene expression and functions as a tumor suppressor in B-cell acute lymphoblastic leukemia (B-ALL). The full cohort of Ikaros target genes have yet to be identified. Here, we demonstrate that Ikaros directly regulates expression of the small GTPase, Rab...

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Pubblicato in:Int J Mol Sci
Autori principali: Payne, Jonathon L, Song, Chunhua, Ding, Yali, Dhanyamraju, Pavan Kumar, Bamme, Yevgeniya, Schramm, Joseph W, Desai, Dhimant, Sharma, Arati, Gowda, Chandrika, Dovat, Sinisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084408/
https://ncbi.nlm.nih.gov/pubmed/32138279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051718
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