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Regulation of cellular proliferation in acute lymphoblastic leukemia by Casein Kinase II (CK2) and Ikaros

The IKZF1 gene encodes the Ikaros protein, a zinc finger transcriptional factor that acts as a master regulator of hematopoiesis and a tumor suppressor in leukemia. Impaired activity of Ikaros is associated with the development of high-risk acute lymphoblastic leukemia (ALL) with a poor prognosis. T...

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書目詳細資料
發表在:Adv Biol Regul
Main Authors: Gowda, Chandrika, Song, Chunhua, Kapadia, Malika, Payne, Jonathon L., Hu, Tommy, Ding, Yali, Dovat, Sinisa
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053069/
https://ncbi.nlm.nih.gov/pubmed/27666503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2016.09.003
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