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Extracellular Vesicle-Induced Classical Complement Activation Leads to Retinal Endothelial Cell Damage via MAC Deposition

Several studies have suggested that there is a link between membrane attack complex (MAC) deposition in the retina and the progression of diabetic retinopathy (DR). Our recent investigation demonstrated that circulating IgG-laden extracellular vesicles contribute to an increase in retinal vascular p...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Huang, Chao, Fisher, Kiera P., Hammer, Sandra S., Busik, Julia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084203/
https://ncbi.nlm.nih.gov/pubmed/32121610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051693
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