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Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme
Clostridioides difficile is a Gram-positive, pathogenic bacterium and a prominent cause of hospital-acquired diarrhea in the United States. The symptoms of C. difficile infection are caused by the activity of three large toxins known as toxin A (TcdA), toxin B (TcdB), and the C. difficile transferas...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084131/ https://ncbi.nlm.nih.gov/pubmed/32123082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920555117 |
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