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Cyp2c44 regulates prostaglandin synthesis, lymphangiogenesis, and metastasis in a mouse model of breast cancer
Arachidonic acid epoxides generated by cytochrome P450 (CYP) enzymes have been linked to increased tumor growth and metastasis, largely on the basis of overexpression studies and the application of exogenous epoxides. Here we studied tumor growth and metastasis in Cyp2c44(−/−) mice crossed onto the...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084120/ https://ncbi.nlm.nih.gov/pubmed/32123095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921381117 |
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