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Frameshifting preserves key physicochemical properties of proteins

Frameshifts in protein coding sequences are widely perceived as resulting in either nonfunctional or even deleterious protein products. Indeed, frameshifts typically lead to markedly altered protein sequences and premature stop codons. By analyzing complete proteomes from all three domains of life,...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bartonek, Lukas, Braun, Daniel, Zagrovic, Bojan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084103/
https://ncbi.nlm.nih.gov/pubmed/32127487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911203117
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