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Integrated structural and evolutionary analysis reveals common mechanisms underlying adaptive evolution in mammals

Understanding the molecular basis of adaptation to the environment is a central question in evolutionary biology, yet linking detected signatures of positive selection to molecular mechanisms remains challenging. Here we demonstrate that combining sequence-based phylogenetic methods with structural...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Slodkowicz, Greg, Goldman, Nick
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084095/
https://ncbi.nlm.nih.gov/pubmed/32123117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916786117
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