Sonoselective transfection of cerebral vasculature without blood–brain barrier disruption

Treatment of many pathologies of the brain could be improved markedly by the development of noninvasive therapeutic approaches that elicit robust, endothelial cell-selective gene expression in specific brain regions that are targeted under MR image guidance. While focused ultrasound (FUS) in conjunc...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gorick, Catherine M., Mathew, Alexander S., Garrison, William J., Thim, E. Andrew, Fisher, Delaney G., Copeland, Caitleen A., Song, Ji, Klibanov, Alexander L., Miller, G. Wilson, Price, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Physical Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084076/
https://ncbi.nlm.nih.gov/pubmed/32123081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914595117
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