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sgRNA-PSM: Predict sgRNAs On-Target Activity Based on Position-Specific Mismatch

As a key technique for the CRISPR-Cas9 system, identification of single-guide RNAs (sgRNAs) on-target activity is critical for both theoretical research (investigation of RNA functions) and real-world applications (genome editing and synthetic biology). Because of its importance, several computation...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Liu, Bin, Luo, Zhihua, He, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083770/
https://ncbi.nlm.nih.gov/pubmed/32199128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.029
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