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Elimination of Specific miRNAs by Naked 14-nt sgRNAs
tRNase Z(L)-utilizing efficacious gene silencing (TRUE gene silencing) is a newly developed technology to suppress mammalian gene expression. TRUE gene silencing works on the basis of a unique enzymatic property of mammalian tRNase Z(L), which is that it can recognize a pre-tRNA-like or micro-pre-tR...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366928/ https://ncbi.nlm.nih.gov/pubmed/22675569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038496 |
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