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MicroRNA-1224-5p Inhibits Metastasis and Epithelial-Mesenchymal Transition in Colorectal Cancer by Targeting SP1-Mediated NF-κB Signaling Pathways

MicroRNAs (miRNAs) are small non-coding RNAs that play pivotal roles in cancer initiation and progression. However, the roles and molecular mechanisms of miRNAs in colorectal cancer (CRC) progression remain unclear. Here, we show that downregulation of miR-1224-5p in CRC is negatively correlated wit...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Li, Jie, Peng, Wen, Yang, Peng, Chen, Ranran, Gu, Qiou, Qian, Wenwei, Ji, Dongjian, Wang, Qingyuan, Zhang, Zhiyuan, Tang, Junwei, Sun, Yueming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083241/
https://ncbi.nlm.nih.gov/pubmed/32231999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00294
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