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Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

BACKGROUND: m6A modification has been proved to play an important role in many biological processes. METTL3 as the main methyltransferase for methylation process has been found to be upregulated in many cancers, including CRC. Here, we investigate m6A modification and the underlying mechanism of MET...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Exp Clin Cancer Res
Main Authors: Peng, Wen, Li, Jie, Chen, Ranran, Gu, Qiou, Yang, Peng, Qian, Wenwei, Ji, Dongjian, Wang, Qingyuan, Zhang, Zhiyuan, Tang, Junwei, Sun, Yueming
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729001/
https://ncbi.nlm.nih.gov/pubmed/31492150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1408-4
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