Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

BACKGROUND: m6A modification has been proved to play an important role in many biological processes. METTL3 as the main methyltransferase for methylation process has been found to be upregulated in many cancers, including CRC. Here, we investigate m6A modification and the underlying mechanism of MET...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Peng, Wen, Li, Jie, Chen, Ranran, Gu, Qiou, Yang, Peng, Qian, Wenwei, Ji, Dongjian, Wang, Qingyuan, Zhang, Zhiyuan, Tang, Junwei, Sun, Yueming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729001/
https://ncbi.nlm.nih.gov/pubmed/31492150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1408-4
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