Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously demonstrated that a piperidinol d...

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Vydáno v:ChemistryOpen
Hlavní autoři: de Ruyck, Jérôme, Dupont, Christian, Lamy, Elodie, Le Moigne, Vincent, Biot, Christophe, Guérardel, Yann, Herrmann, Jean‐Louis, Blaise, Mickaël, Grassin‐Delyle, Stanislas, Kremer, Laurent, Dubar, Faustine
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083170/
https://ncbi.nlm.nih.gov/pubmed/32211280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000042
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