Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously demonstrated that a piperidinol d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ChemistryOpen
Prif Awduron: de Ruyck, Jérôme, Dupont, Christian, Lamy, Elodie, Le Moigne, Vincent, Biot, Christophe, Guérardel, Yann, Herrmann, Jean‐Louis, Blaise, Mickaël, Grassin‐Delyle, Stanislas, Kremer, Laurent, Dubar, Faustine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Full Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083170/
https://ncbi.nlm.nih.gov/pubmed/32211280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000042
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