Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously demonstrated that a piperidinol d...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: de Ruyck, Jérôme, Dupont, Christian, Lamy, Elodie, Le Moigne, Vincent, Biot, Christophe, Guérardel, Yann, Herrmann, Jean‐Louis, Blaise, Mickaël, Grassin‐Delyle, Stanislas, Kremer, Laurent, Dubar, Faustine
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083170/
https://ncbi.nlm.nih.gov/pubmed/32211280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202000042
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