Characterization of astrocytes throughout life in wildtype and APP/PS1 mice after early-life stress exposure

BACKGROUND: Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model. Because astrocytes are key players in the pathog...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Abbink, Maralinde R., Kotah, Janssen M., Hoeijmakers, Lianne, Mak, Aline, Yvon-Durocher, Genevieve, van der Gaag, Bram, Lucassen, Paul J., Korosi, Aniko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083036/
https://ncbi.nlm.nih.gov/pubmed/32197653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01762-z
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