Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications

BACKGROUND: Sequencing artifacts, clonal hematopoietic mutations of indeterminate potential (CHIP) and tumor heterogeneity have been hypothesized to contribute to the low concordance between tissue and cell-free DNA (cfDNA) molecular profiling with targeted sequencing. METHODS: We analyzed by target...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Pasquale, Raffaella, Forgione, Laura, Roma, Cristin, Fenizia, Francesca, Bergantino, Francesca, Rachiglio, Anna M., De Luca, Antonella, Gallo, Marianna, Maiello, Monica R., Palumbo, Giuliano, Morabito, Alessandro, Azzaro, Rosa, Normanno, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082281/
https://ncbi.nlm.nih.gov/pubmed/32206554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2020.01.01
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