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Quaternary β(2,2)-amino acid derivatives by asymmetric addition of isoxazolidin-5-ones to para-quinone methides†
The highly enantioselective (>99.5% ee) synthesis of a new class of densely functionalized β(2,2)-amino acid derivatives by reacting isoxazolidin-5-ones with para-quinone methides in the presence of chiral ammonium salt phase-transfer catalysts was developed. The reaction proceeds with exceptiona...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082149/ https://ncbi.nlm.nih.gov/pubmed/31830176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc09239k |
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