A Genome-Wide CRISPR-Cas9 Screen Identifies the Dolichol-Phosphate Mannose Synthase Complex as a Host Dependency Factor for Dengue Virus Infection

Dengue virus (DENV) is a mosquito-borne flavivirus responsible for dengue disease, a major human health concern for which no specific therapies are available. Like other viruses, DENV relies heavily on the host cellular machinery for productive infection. In this study, we performed a genome-wide CR...

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Vydáno v:J Virol
Hlavní autoři: Labeau, Athena, Simon-Loriere, Etienne, Hafirassou, Mohamed-Lamine, Bonnet-Madin, Lucie, Tessier, Sarah, Zamborlini, Alessia, Dupré, Thierry, Seta, Nathalie, Schwartz, Olivier, Chaix, Marie-Laure, Delaugerre, Constance, Amara, Ali, Meertens, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081898/
https://ncbi.nlm.nih.gov/pubmed/31915280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01751-19
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