Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

BACKGROUND: Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine carcinoma of the skin caused by either the integration of Merkel cell polyomavirus (MCPyV) and expression of viral T antigens or by ultraviolet-induced damage to the tumor genome from excessive sunlight exposure. An increa...

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Bibliografiske detaljer
Udgivet i:Genome Med
Main Authors: Starrett, Gabriel J., Thakuria, Manisha, Chen, Tianqi, Marcelus, Christina, Cheng, Jingwei, Nomburg, Jason, Thorner, Aaron R., Slevin, Michael K., Powers, Winslow, Burns, Robert T., Perry, Caitlin, Piris, Adriano, Kuo, Frank C., Rabinowits, Guilherme, Giobbie-Hurder, Anita, MacConaill, Laura E., DeCaprio, James A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081548/
https://ncbi.nlm.nih.gov/pubmed/32188490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00727-4
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