Pyruvate Kinase Muscle Isoenzyme 2 (PKM2) Expression Is Associated with Overall Survival in Pancreatic Ductal Adenocarcinoma

PURPOSE: Pyruvate kinase muscle isoenzyme 2 (PKM2) is a key enzyme in aerobic glycolysis and is thought to contribute to cancer cell metabolic reprogramming. The aim of this study was to evaluate PKM2 immunohistochemical expression as a potential prognostic biomarker in pancreatic ductal adenocarcin...

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Bibliografiset tiedot
Julkaisussa:J Gastrointest Cancer
Päätekijät: Lockney, Natalie A., Zhang, Manchao, Lu, Yanzhen, Sopha, Sabrina C., Washington, M. Kay, Merchant, Nipun, Zhao, Zhiguo, Shyr, Yu, Chakravarthy, A. Bapsi, Xia, Fen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081381/
https://ncbi.nlm.nih.gov/pubmed/26385349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12029-015-9764-6
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