Whole genome analysis identifies the association of TP53 genomic deletions with lower survival in Stage III colorectal cancer

DNA copy number aberrations (CNA) are frequently observed in colorectal cancers (CRC). There is an urgent need for CNA-based biomarkers in clinics,. n For Stage III CRC, if combined with imaging or pathologic evidence, these markers promise more precise care. We conducted this Stage III specific bio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xia, Li C., Van Hummelen, Paul, Kubit, Matthew, Lee, HoJoon, Bell, John M., Grimes, Susan M., Wood-Bouwens, Christina, Greer, Stephanie U., Barker, Tyler, Haslem, Derrick S., Ford, James M., Fulde, Gail, Ji, Hanlee P., Nadauld, Lincoln D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081316/
https://ncbi.nlm.nih.gov/pubmed/32193467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61643-6
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