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Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target

Direct-acting antivirals are effective tools to control viral infections. SARS-CoV-2 is a coronavirus associated with the epidemiological outbreak in late 2019. Previous reports showed that HIV-1 protease inhibitors could block SARS-CoV main protease. Based on that and using an in silico approach, w...

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Publicat a:EXCLI J
Autors principals: Ortega, Joseph Thomas, Serrano, Maria Luisa, Pujol, Flor Helene, Rangel, Hector Rafael
Format: Artigo
Idioma:Inglês
Publicat: Leibniz Research Centre for Working Environment and Human Factors 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081067/
https://ncbi.nlm.nih.gov/pubmed/32210741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-1189
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