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Mutations in the SARS-CoV-2 spike protein modulate the virus affinity to the human ACE2 receptor, an in silico analysis

The increasing number of SARS-CoV-2 variants associated with highly transmissible phenotypes is a health-public concern in the current pandemic scenario. Herein, we developed a comprehensive in silico analysis of the changes occurring upon mutations in the viral spike. We focused on mutants located...

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Podrobná bibliografie
Vydáno v:EXCLI J
Hlavní autoři: Ortega, Joseph Thomas, Pujol, Flor Helene, Jastrzebska, Beata, Rangel, Hector R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Leibniz Research Centre for Working Environment and Human Factors 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056063/
https://ncbi.nlm.nih.gov/pubmed/33883984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2021-3471
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