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Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors
Tyrosine-kinase inhibitors (TKIs) demonstrate high inter-individual variability with respect to safety and efficacy and would therefore benefit from dose or schedule adjustments. This study investigated the efficacy, safety, and economical aspects of alternative dosing options for sunitinib in gastr...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7080977/ https://ncbi.nlm.nih.gov/pubmed/32226388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00316 |
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