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Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

Tyrosine-kinase inhibitors (TKIs) demonstrate high inter-individual variability with respect to safety and efficacy and would therefore benefit from dose or schedule adjustments. This study investigated the efficacy, safety, and economical aspects of alternative dosing options for sunitinib in gastr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Centanni, Maddalena, Friberg, Lena E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080977/
https://ncbi.nlm.nih.gov/pubmed/32226388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00316
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