RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells

The cardinal virulence factor of human-pathogenic enterohaemorrhagic Escherichia coli (EHEC) is Shiga toxin (Stx), which causes severe extraintestinal complications including kidney failure by damaging renal endothelial cells. In EHEC pathogenesis, the disturbance of the kidney epithelium by Stx bec...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kouzel, Ivan U., Kehl, Alexander, Berger, Petya, Liashkovich, Ivan, Steil, Daniel, Makalowski, Wojciech, Suzuki, Yutaka, Pohlentz, Gottfried, Karch, Helge, Mellmann, Alexander, Müthing, Johannes
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080763/
https://ncbi.nlm.nih.gov/pubmed/32188865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59694-w
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki