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Shiga Toxin (Stx)-Binding Glycosphingolipids of Primary Human Renal Cortical Epithelial Cells (pHRCEpiCs) and Stx-Mediated Cytotoxicity

Human kidney epithelial cells are supposed to be directly involved in the pathogenesis of the hemolytic–uremic syndrome (HUS) caused by Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC). The characterization of the major and minor Stx-binding glycosphingolipids (GSLs) globotriaos...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Detzner, Johanna, Krojnewski, Elisabeth, Pohlentz, Gottfried, Steil, Daniel, Humpf, Hans-Ulrich, Mellmann, Alexander, Karch, Helge, Müthing, Johannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918848/
https://ncbi.nlm.nih.gov/pubmed/33673393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13020139
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