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Novel strategies for expansion of tooth epithelial stem cells and ameloblast generation

Enamel is secreted by ameloblasts derived from tooth epithelial stem cells (SCs). Humans cannot repair or regenerate enamel, due to early loss of tooth epithelial SCs. Contrarily in the mouse incisors, epithelial SCs are maintained throughout life and endlessly generate ameloblasts, and thus enamel....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Binder, Martin, Biggs, Leah C., Kronenberg, Mark S., Schneider, Pascal, Thesleff, Irma, Balic, Anamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080756/
https://ncbi.nlm.nih.gov/pubmed/32188889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60708-w
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