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Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors

The continuously growing mouse incisor serves as a valuable model to study stem cell regulation during organ renewal. Epithelial stem cells are localized in the proximal end of the incisor in the labial cervical loop. Here, we show that the transcription factor Sox2 is a specific marker for these st...

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Detalhes bibliográficos
Main Authors: Juuri, Emma, Saito, Kan, Ahtiainen, Laura, Seidel, Kerstin, Tummers, Mark, Hochedlinger, Konrad, Klein, Ophir D., Thesleff, Irma, Michon, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690347/
https://ncbi.nlm.nih.gov/pubmed/22819339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.012
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