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Dispersion from C(α) or N(H): 4D experiments for backbone resonance assignment of intrinsically disordered proteins

Resonance assignment of intrinsically disordered proteins is remarkably challenging due to scant chemical shift dispersion arising from conformational heterogeneity. The challenge is even greater if repeating segments are present in the amino acid sequence. To forward unambiguous resonance assignmen...

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Tossavainen, Helena, Salovaara, Santeri, Hellman, Maarit, Ihalin, Riikka, Permi, Perttu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080685/
https://ncbi.nlm.nih.gov/pubmed/31932991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00299-w
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