Intravascular adhesion and recruitment of neutrophils in response to CXCL1 depends on their TRPC6 channels

ABSTRACT: Here we report a novel role for TRPC6, a member of the transient receptor potential (TRPC) channel family, in the CXCL1-dependent recruitment of murine neutrophil granulocytes. Representing a central element of the innate immune system, neutrophils are recruited from the blood stream to a...

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Bibliografske podrobnosti
izdano v:J Mol Med (Berl)
Main Authors: Lindemann, Otto, Rossaint, Jan, Najder, Karolina, Schimmelpfennig, Sandra, Hofschröer, Verena, Wälte, Mike, Fels, Benedikt, Oberleithner, Hans, Zarbock, Alexander, Schwab, Albrecht
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080674/
https://ncbi.nlm.nih.gov/pubmed/31950205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01872-4
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