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Efficacy and safety of PARP inhibitors as the maintenance therapy in ovarian cancer: a meta-analysis of nine randomized controlled trials

Purpose: Poly ADP ribose polymerase (PARP) inhibitors can effectively kill cancer cells by restraining the activity of DNA repair enzymes and utilizing the characteristics of BRCA mutations. This article evaluates the efficacy and safety of PARP inhibitors (PARPis) in the maintenance treatment of ov...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Main Authors: Shao, Fengping, Liu, Jun, Duan, Yaoyun, Li, Li, Liu, Liqun, Zhang, Cai, He, Shanyang
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080644/
https://ncbi.nlm.nih.gov/pubmed/32096544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192226
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