Efficacy and safety of PARP inhibitors as the maintenance therapy in ovarian cancer: a meta-analysis of nine randomized controlled trials

Purpose: Poly ADP ribose polymerase (PARP) inhibitors can effectively kill cancer cells by restraining the activity of DNA repair enzymes and utilizing the characteristics of BRCA mutations. This article evaluates the efficacy and safety of PARP inhibitors (PARPis) in the maintenance treatment of ov...

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Udgivet i:Biosci Rep
Main Authors: Shao, Fengping, Liu, Jun, Duan, Yaoyun, Li, Li, Liu, Liqun, Zhang, Cai, He, Shanyang
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2020
Fag:
Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080644/
https://ncbi.nlm.nih.gov/pubmed/32096544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192226
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