Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance

Biofilm-associated prosthetic joint infections (PJIs) cause significant morbidity due to their recalcitrance to immune-mediated clearance and antibiotics, with Staphylococcus aureus (S. aureus) among the most prevalent pathogens. We previously demonstrated that S. aureus biofilm-associated monocytes...

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Publicado en:PLoS Pathog
Autores principales: Yamada, Kelsey J., Heim, Cortney E., Xi, Xinyuan, Attri, Kuldeep S., Wang, Dezhen, Zhang, Wenting, Singh, Pankaj K., Bronich, Tatiana K., Kielian, Tammy
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080272/
https://ncbi.nlm.nih.gov/pubmed/32142554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008354
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